If you have a high-res, large monitor, you want to arrange your windows like a grid. You don't want to actually use Google Chrome at full 4k with no scaling across the entire screen.

I mostly grid at 42" (moom is awesome)... still have to move my head. The mac/ubuntu top menu is a bit annoying on a really big display. Still prefer it to a couple smaller screens.

Still have to move your head. My 24 is big enough to require a modest amount of movement.