Yes and no. Lying in routine questioning isn't obstruction of justice until an investigation is underway. It would fall under the right to not self-incriminate otherwise a cop could just walk the street and ask everyone "do you smoke pot?". You also have the right not to self incriminate on an obstruction of justice charge!

Basically the closer you get to a jury and a judge the worse the charge for lying is. So if lying stands a good chance of keeping you far far away, you lie your ass off.