"There are now dozens of large applications written by teams in Microsoft, including Bing, Xbox, TFS, So.cl, as well as in projects such as Adobe Digital Publishing Suite for Windows 8.1, Zud.io, Away3D, and Turbulenz."
I think they've been pretty serious about it from the start due to the design decisions in Metro.
For me that elevates TypeScript from a MS side project to something they're serious about.