Knowledge is being aware of the analogy of tomatoes not being treated like fruits even though they technically are.
Wisdom is understanding that if there was legislation on the matter, and people who ate, produced, or sold non-tomato fruits were hunted and deprived of their freedoms by the state on the basis that fruits are bad for society, then you would likely see similar frustrations expressed about an article title that includes the phrase "tomatoes and fruits" to distinguish them.
Alcohol in moderation is relaxing. Most drugs, OTOH, when used at the doses that make them attractive to recreational drug users, impair reason, and impairing reason is not just stupid, but immoral. We can debate the particular methods by which the state regulates or otherwise deals with drug use, but there is nothing intrinsically wrong with the criminalization of such drugs as such. No one has a right to take drugs (there is no right to immorality). This may seem alien to a culture whose emaciated understanding of morality is exhausted by the concept of consent. The law is a teacher, and it is good to teach people that recreational drug use (and drunkenness) is a bad thing. Like all immorality, it is an insult to one's dignity and humanity.
We can tolerate the impairment of reason as a proportionate side effect [0] (for instance, high doses of morphine given to terminally ill patients in extreme pain), but this is not recreational use.
Wisdom is understanding that if there was legislation on the matter, and people who ate, produced, or sold non-tomato fruits were hunted and deprived of their freedoms by the state on the basis that fruits are bad for society, then you would likely see similar frustrations expressed about an article title that includes the phrase "tomatoes and fruits" to distinguish them.