Besides being much slower, and taking up much more space per environment, than uv, conda also has a nasty habit of causing unrelated things to break in weird ways. I've mostly stopped using it at this point, for that reason, tho I've still had to reach for it on occasion. Maybe pixi can replace those use cases. I really should give it a try.
There's also the issue the license for using the repos, which makes it risky to rely on conda/anaconda. See e.g. https://stackoverflow.com/a/74762864
Not sure what you mean about space. Conda uses hardlinks for the most part, so environment size is shared (although disk usage tools don't always correctly report this).
There's also the issue the license for using the repos, which makes it risky to rely on conda/anaconda. See e.g. https://stackoverflow.com/a/74762864