We as humans and programmers are creatures of habit, Unity by being a relatively new technology will break some habits in our work ritual. Give it a few years and nobody will complain about this.
I found Unity awkward at first, but I put in a few days' honest effort to learn to shortcuts and try to work as the designers intended me to, and it improved my desktop efficiency quite a bit, and removed a fair bit of clutter compared to Gnome 2. I like Gnome Shell too for the same reasons.
That said, Unity was buggy in 11.04, and only somewhat less so in 11.10, and I still find myself having to occasionally escape to a terminal and restart Unity after it freezes up. I'm hoping 12.04 is better.
They lost me to Mint in their last couple of releases.